Male Parathyroid System Effects of Chronic High-Dose Nandrolone Decanoate

  • Archana Sahu Assistant Professor, Department of Pharmacy, Usha Martin University, Ranchi- Jharkhand
  • Licha Rin Assistant Professor, Department of Pharmacy, Himalayan University, Itanagar-Arunachal Pradesh
  • Devendra Singh Assistant Professor, Department of Pharmacy, Mangalayatan University, Aligarh, Uttar Pradesh
  • Suraj Sharma Associate Professor, Collage of Pharmacy, Sikkim Professional University, Gangtok, Sikkim
Keywords: Rats, Haematological markers Nandrolone decanoate, male hormone

Abstract

Background: Athletes abuse AAS. Objectives: The current research evaluated chronic ND treatment on parathyroidsystem and haematological markers in ratsmale. Techniques: Ten Wistar-Albino male rats each will be in the test,control, and placebo groups. T Group got IM ND 15 mg/kg for 8 weeks. P group got similar amount in oilof peanut, whereas Cgroup could not. Animals were sedated, slaughtered, and cervical blood samples were taken. Using a gonadotropins susceptible rat kit and ELISA, FSH and LH levels were assessed. Laboratory procedures examined serum testosterone and haematological parameters. Data was analysed in SPSS version 17 byTukey testand ANOVA test. Results are MeanStvD. P 0.05 statistically significant. Group T had substantially lower testosterone, LH, FSH, weight growth, food, and water consumption (P 0.05). Group T had considerably more erythrocytes, leucocytes, haemoglobin, and hematocrit (P 0.05). High dosages of ND may change male rats' FSH, LH, testosterone, and haematological markers.

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Published
2022-11-25
How to Cite
Archana Sahu, Licha Rin, Devendra Singh, & Suraj Sharma. (2022). Male Parathyroid System Effects of Chronic High-Dose Nandrolone Decanoate. Revista Electronica De Veterinaria, 23(4), 58 - 61. Retrieved from https://veterinaria.org/index.php/REDVET/article/view/275