Effect of Kaempferia Parviflora on Male Rat Sexual Activity and Its Toxicity

Abstract

Males have used Kaempferia parviflora Wall. Ex. Baker (Krachaidum) to increase their sex enhancement since antiquity. Themain aim is to investigate the effects of a K. parviflora ethanolic extract on the toxicity and sex behaviour of male rats. Three groups of rats received dosages of K. parviflora extract of 60, 120, 240 mg/kg body wt.2months, while the fourth set received distill water. With exception of the set that received maximum amount of extract, male rats in every setshowed significantly superior courtship behaviour within initial observation time than during the second and third 10-minute observation time combined. They displayed the same little courtship behaviour during the whole 30-minute activity, which was much less than the control group. There were no noticeable differences in mount and intromission frequency, mount and intromission latency amongwith treatment and control sets (IL). Blood parameters did not show significant variation in toxicologicalwork. Normal levels of aspartate aminotransferase, alanine aminotransferase, urea, and creatinine indicate that renal and liver function were not compromised at any of the dosages tested. Histology, however, revealed structural alterations inside the liver. The initial ten minutes of courting behaviour in rats was shown to be shortened by plant extracts at higher dose; hence, high and extended doses of this plant should be avoided in people at initial time.