Antibiotic Resistance Patterns in Oral microbial Biofilms: A Study Differentiating Diabetic and Nondiabetic Populations.

  • Pooja Jha
  • Vandana
  • M. Siddhartath
  • Dr. Kunal Kishor
  • Farha Azmeen
Keywords: Antibiotic resistance, Diabetes mellitus, Periodontal disease, Oral Microbiome Analysis, Bacterial proliferation

Abstract

The primary aim of the investigation was to analyze the oral microbiome in patients with diabetic and non-diabetic suffering with periodontitis. Diabetes Mellitus has become a global epidemic illness and poses threat for development of resistant bacterial infections. A total of 100 samples were collected from diabetic and non-diabetic individuals 50 from each group and tested for antibiotic susceptibility. Chi-square tests was conducted to compare the prevalence of each microorganism between the two groups of patient’s samples. A significance level of α = 0.05 was used for all statistical tests, and p-values < 0.05 were considered statistically significant. From all samples, 20 microbial colonies were isolated as per their distinguished colony characteristic, which was further partially identified by biochemical tests. Among all isolates, Chloramphenicol and penicillin resistance is shown by Gram negative bacteria known as Fusobacterium sp.  with highest susceptibility rates. Research shows that bacterial colonization and proliferation in the gingival tissue and the presence of gingival plaques are more common in diabetic patients compared with the control group.

Author Biographies

Pooja Jha

Research Scholar, Department of Microbiology, School of Allied Health Sciences, Sharda University, Greater Noida Uttar Pradesh, India

Vandana

Assistant Professor, Department of Microbiology, School of Allied Health Sciences, Sharda University, Greater Noida, Uttar Pradesh, India

M. Siddhartath

Professor, Department of Microbiology, School of Allied Health Sciences, Sharda University, Greater Noida, Uttar Pradesh, India.

Dr. Kunal Kishor

Professor, Department of Microbiology, School of Allied Health Sciences, Sharda University, Greater Noida, Uttar Pradesh, India.

Farha Azmeen

Research Scholar, Department of Microbiology, School of Allied Health Sciences, Sharda University, Greater Noida Uttar Pradesh, India

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Published
2023-12-29
How to Cite
Pooja Jha, Vandana, M. Siddhartath, Dr. Kunal Kishor, & Farha Azmeen. (2023). Antibiotic Resistance Patterns in Oral microbial Biofilms: A Study Differentiating Diabetic and Nondiabetic Populations. Revista Electronica De Veterinaria, 24(4), 309-319. Retrieved from https://veterinaria.org/index.php/REDVET/article/view/586
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Articles