Surface modified bioactive silicate based material with PRF - regenerative medicine
Abstract
Surface modification is the process of adding bioactive elements to the surface of a silicate to improve its ability to interact with biological systems. These bioactive elements, such as growth factors or peptides, can be used to modify the surface properties of the silicate to enhance its ability to stimulate certain cellular activities. These cellular activities can be used to improve tissue regeneration.
Aim: The aim of the study is to elucidate Surface modified bioactive silicate based material with PRF - regenerative medicine
Materials and method: Use a range of analytical methods to describe the altered substance. This comprises Fourier-transform infrared spectroscopy (FTIR) for chemical composition, X-ray diffraction (XRD) for crystalline phases, and scanning electron microscopy (SEM) for surface morphology.
Results: PRF is a strong contender for translational applications due to its ability to promote cell adhesion, proliferation, and tissue integration.
Conclusion: The combination of Platelet-Rich Fibrin (PRF) with a surface-modified bioactive silicate-based material is encouraging for the field of regenerative medicine.
References
2. Kushihiki N, Yamaguchi K, K. SDK. Surface Modification of Silicate Base Material. 1986. 6 p.
3. Wang Y. Surface Modification of Silicate Substrates. 2007. 134 p.
4. Singh N, Kashyap M. Is Autologous Sticky Bone Better Than a Simple Mixture of Autologous PRF and Bioactive Glass in the Regeneration of Human Periodontal Intrabony Defects? An Extensive Clinical and CBCT Study. Int J Periodontics Restorative Dent. 2023 Oct 24;(7):s264–82.
5. Shanbhag S, Al-Sharabi N, Kampleitner C, Mohamed-Ahmed S, Kristoffersen EK, Tangl S, et al. The use of mesenchymal stromal cell secretome to enhance guided bone regeneration in comparison with leukocyte and platelet-rich fibrin. Clin Oral Implants Res [Internet]. 2023 Nov 14; Available from: http://dx.doi.org/10.1111/clr.14205
6. Liu M, Liu Y, Luo F. The role and mechanism of platelet-rich fibrin in alveolar bone regeneration. Biomed Pharmacother. 2023 Dec;168:115795.
7. Cheng B, Fu X. Platelet-Rich Plasma in Tissue Repair and Regeneration: Technology and transformation application. Springer Nature; 2023. 184 p.
8. Celikten M, Sahin H, Senturk GE, Bilsel K, Pulatkan A, Kapicioglu M, et al. The Effect of Platelet-Rich Fibrin, Platelet-Rich Plasma, and Concentrated Growth Factor in the Repair of Full Thickness Rotator Cuff Tears. J Shoulder Elbow Surg [Internet]. 2023 Oct 26; Available from: http://dx.doi.org/10.1016/j.jse.2023.09.028
9. Liu H, Ding J, Zhao C. Bioactive bone regenerative materials and bionic prosthesis interfaces. Frontiers Media SA; 2023. 317 p.
10. Miron RJ, Choukroun J. Platelet Rich Fibrin in Regenerative Dentistry: Biological Background and Clinical Indications. John Wiley & Sons; 2017. 407 p.

