Meta Analysis and Systematic Review of Various Treatment Options for Maxillary Lateral Incisors Agenesis
Abstract
Background: Maxillary lateral incisor agenesis (MLIA) affects appearance, functionality, and mental health, thereby making therapeutic decisions will be difficult. Healthcare professionals switch between space opening (SO) and space closure (SC) methods, attempting to find the most appropriate strategy for every patient. The aim of this systematic review is to evaluate the functional, cosmetic and long-term stability results of several treatment modalities for maxillofacial instability (MLIA). Specifically, the research will focus on orthodontic space closure, prosthodontic treatments (such as implants and resin-bonded prostheses) and canine relocation.
Methods: Interdisciplinary research methodologies were used to databases from 2009 to 2024, without regard to language constraints, using PRISMA criteria. The inclusion criteria included research on MLIA treatment, omitting cases of tooth loss due to caries, and evaluating results for long-term stability, aesthetics, and functionality.
Results: Of the 2085 papers that were examined, 10 made a direct comparison between orthodontic space closure and prosthodontic intervention and were considered for the review. Orthodontic gap closure was more common than prosthodontic intervention, and the ratio of MLIA incidence was greater in females. Compared to more conventional prosthodontic techniques, implants were utilized less frequently. Periodontal evaluations demonstrated consistent papilla indices and little soft tissue problems, highlighting better orthodontic closure results. Patient satisfaction varied among treatment modalities, and aesthetic judgments were inconsistent.
Conclusion: In conclusion, treatment planning is aided by early identification of MLIA. In order to minimize long-term biological and technical complications while assuring periodontal health, aesthetic outcomes, and early treatment completion throughout adolescence, orthodontic space closure becomes the recommended choice.
References
2. Krassnig M, Fickl S. Congenitally Missing Lateral Incisors—A Comparison Between Restorative, Implant, and Orthodontic Approaches. Dental Clinics of North America 2011;55:283–99. https:// doi.org/10.1016 /j.cden.2011.01.004.
3. Arte S, Nieminen P, Apajalahti S, Haavikko K, Thesleff I, Pirinen S. Characteristics of Incisor-Premolar Hypodontia in Families. Journal of Dental Research 2001;80:1445–50. https://doi.org/10.1177/00220345010800051201.
4. Prevalence of Congenitally Missing Permanent Teeth in Aseer, KSA. Journal of Oral & Dental Health 2017;1. https://doi.org/10.33140/jodh/01/02/00006.
5. V V-R, M M, Z M. Prevalence of Dental Anomalies in Deciduous Teeth and their Correlation with the Permanent Dentition: Double Teeth, Hypodontia and Hyperdontia. International Journal of Dentistry and Oral Health 2019;5. https://doi.org/10.16966/2378-7090.292.
6. Goya HA, Tanaka S, Maeda T, Akimoto Y. An orthopantomographic study of hypodontia in permanent teeth of Japanese pediatric patients. Journal of Oral Science 2008;50:143–50. https://doi.org/10.2334/josnusd.50.143.
7. Shimizu T, Maeda T. Prevalence and genetic basis of tooth agenesis. Japanese Dental Science Review 2009;45:52–8. https://doi.org/10.1016/j.jdsr.2008.12.001.
8. Alves-Ferreira M, Pinho T, Sousa A, Sequeiros J, Lemos C, Alonso I. Identification of Genetic Risk Factors for Maxillary Lateral Incisor Agenesis. Journal of Dental Research 2014;93:452–8. https://doi.org /10.1177 /0022034514523986.
9. S S. Orthodontically Replacement of Canine with Congenitally Missing Maxillary Lateral Incisor – A Case Report. Medical Journal of Clinical Trials & Case Studies 2018;2. https://doi.org/10.23880/mjccs-16000149.
10. Millet C, Viennot S, Duprez JP. Case report: Rehabilitation of a child with dentinogenesis imperfecta and congenitally missing lateral incisors. European Archives of Paediatric Dentistry 2010;11:256–60. https://doi.org/10.1007/bf03262758.
11. Branzén M, Eliasson A, Arnrup K, Bazargani F. Implant‐Supported Single Crowns Replacing Congenitally Missing Maxillary Lateral Incisors: A 5‐Year Follow‐Up. Clinical Implant Dentistry and Related Research 2014;17:1134–40. https://doi.org/10.1111/cid.12233.
12. Simeone P, De Paoli C, De Paoli S, Leofreddi G, Sgrò S. Interdisciplinary Treatment Planning for Single‐Tooth Restorations in the Esthetic Zone. Journal of Esthetic and Restorative Dentistry 2007;19:79–88. https://doi.org/10.1111/j.1708-8240.2007.00071.x.
13. De-Marchi LM, Pini NIP, Ramos AL, Pascotto RC. Smile attractiveness of patients treated for congenitally missing maxillary lateral incisors as rated by dentists, laypersons, and the patients themselves. The Journal of Prosthetic Dentistry 2014;112:540–6. https://doi.org/10.1016/j.prosdent.2014.01.019.
14. Nordquist GG, McNeill RW. Orthodontic vs. Restorative Treatment of the Congenitally Absent Lateral Incisor—Long Term Periodontal and Occlusal Evaluation. Journal of Periodontology 1975;46:139–43. https://doi.org/10.1902/jop.1975.46.3.139.
15. Robertsson S. The congenitally missing upper lateral incisor. A retrospective study of orthodontic space closure versus restorative treatment. The European Journal of Orthodontics 2000;22:697–710. https: //doi.org /10.1093/ejo/22.6.697.
16. Jamilian A, Perillo L, Rosa M. Missing upper incisors: a retrospective study of orthodontic space closure versus implant. Progress in Orthodontics 2015;16. https://doi.org/10.1186/s40510-015-0072-2.
17. Branzén M, Eliasson A, Arnrup K, Bazargani F. Implant‐Supported Single Crowns Replacing Congenitally Missing Maxillary Lateral Incisors: A 5‐Year Follow‐Up. Clinical Implant Dentistry and Related Research 2014;17:1134–40. https://doi.org/10.1111/cid.12233.
18. Garnett MJ, Wassell RW, Jepson NJ, Nohl FS. Survival of resin-bonded bridgework provided for post-orthodontic hypodontia patients with missing maxillary lateral incisors. British Dental Journal 2006;201:527–34. https://doi.org/10.1038/sj.bdj.4814160.
19. Mangano C, Levrini L, Mangano A, Mangano F, Macchi A, Caprioglio A. Esthetic Evaluation of Implants Placed after Orthodontic Treatment in Patients with Congenitally Missing Lateral Incisors. Journal of Esthetic and Restorative Dentistry 2013;26:61–71. https://doi.org/10.1111/jerd.12081.
20. Peñarrocha M, Lamas J, Peñarrocha M, Garcia B. Immediate Maxillary Lateral Incisor Implants with Nonocclusal Loading Provisional Crowns. Journal of Prosthodontics 2007;17:55–9. https://doi.org/10.1111/j.1532-849x.2007.00242.x.
21. Sailer I, Bonani T, Brodbeck U, Hammerle C. Retrospective Clinical Study of Single-Retainer Cantilever Anterior and Posterior Glass-Ceramic Resin-Bonded Fixed Dental Prostheses at a Mean Follow-up of 6 Years. International Journal of Prosthodontics 2013;26:443–50. https://doi.org/10.11607/ijp.3368.
22. Zarone F, Sorrentino R, Vaccaro F, Russo S. Prosthetic treatment of maxillary lateral incisor agenesis with osseointegrated implants: a 24–39‐month prospective clinical study. Clinical Oral Implants Research 2006;17:94–101. https://doi.org/10.1111/j.1600-0501.2005.01188.x.
